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Objective To observe the clinical effect of electric acupuncture,surrounding acupuncture and cotton moxibustion in the treatment of herpes zoster.Methods Forty cases with herpes zoster were randomly divided into a treatment group and a control group,with 20 patients in each group.The treatment group was treated with electric acupuncture,surrounding acupuncture and cotton moxibustion,while the control group was treated with valaciclovir and vitamin B1.In the two groups severity of pain and the time of pain beginning to ease,pain lasting blisters disappearing,incrustation and decrustation during treatment were observed and recorded,referring to the People's Republic of China Traditional Chinese Medicine Industry Standard(Chinese disease diagnosis and efficacy standard)for efficacy evaluation.Results There was significant difference between the treatment group and the control group with regard to the cure rate(75% versus 35%,P＜0.05);however,the total effective rates of two groups had no significant difference(P＞0.05).After treatment VAS score in treatment group was significantly lower than that in control group(P＜0.05);in treatment group the time of pain beginning to ease and pain lasting were significantly less than those in control group(P＜0.05);the time of blister disappearing in treatment group was significantly faster than that in control group(P＜0.01);the time of incrustation and decrustation in treatment group were significantly less than those in control group(P＜0.05).Conclusion The advantages of electric acupuncture,surrounding acupuncture and cotton moxibustion in the treatment of herpes zoster were shown as faster pain easing,shorter pain lasting,shorter duration of blister and incrustation.This treatment for herpes zoster is safe,effective and affordable.
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The changes in the levels of serum interleukin-13 (IL-13) and nerve growth factor (NGF) in patients with systemic lupus erythematosus (SLE) and their clinical significance were investigated. Sandwich ELISA was used to determine the levels of serum IL-13 and NGF in 35 SLE patients and 15 normal controls. The results showed that the levels of serum IL-13 (92.69+/-9.87 pg/ml) and NGF (339.69+/-25.60 pg/ml) in active SLE patients were significantly higher than those in inactive SLE patients (IL-13, 54.22+/-9.31 pg/ml; NGF, 300.89+/-33.51 pg/ml) (P<0.01). The inactive patients also had significantly increased serum levels of IL-13 and NGF as compared with normal controls (IL-13, 35.20+/-12.70 pg/ml; NGF, 111.40+/-32.54 pg/ml; P<0.05 and P<0.01, respectively). Spearman correlation analysis revealed that the serum IL-13 levels were correlated with disease activity index of SLE (SLEDAI), ESR and serum levels of C3 (r= 0. 813, 0.504, -0.605, respectively). The serum NGF levels were also correlated with above markers (r=0.442, 0.338, -0.463, respectively). The serum levels of IL-13 and NGF had a positive correlation (r=0.506, P<0.01). It was suggested that IL-13 and NGF might be involved in the pathogenesis of SLE and closely correlated with disease activity.
Subject(s)
Enzyme-Linked Immunosorbent Assay/methods , Interleukin-13/blood , Lupus Erythematosus, Systemic/blood , Lupus Erythematosus, Systemic/etiology , Nerve Growth Factors/bloodABSTRACT
Summary: The changes in the levels of serum interleukin-13 (IL-13) and nerve growth factor (NGF) in patients with systemic lupus erythematosus (SLE) and their clinical significance were investigated. Sandwich ELISA was used to determine the levels of serum IL-13 and NGF in 35 SLE patients and 15 normal controls. The results showed that the levels of serum IL-13 (92.69±9.87 pg/ml) and NGF (339.69±25.60 pg/ml) in active SLE patients were significantly higher than those in inactive SLE patients (IL-13, 54.22±9.31 pg/ml; NGF, 300.89±33.51 pg/ml)(P<0.01). The inactive patients also had significantly increased serum levels of IL-13 and NGF as compared with normal controls (IL-13, 35.20±12.70 pg/ml; NGF, 111.40±32.54 pg/ml; P<0.05 and P<0.01, respectively). Spearman correlation analysis revealed that the serum IL-13 levels were correlated with disease activity index of SLE (SLEDAI), ESR and serum levels of C3 (r= 0.813, 0.504, -0.605, respectively). The serum NGF levels were also correlated with above markers (r=0.442, 0.338, -0.463, respectively). The serum levels of IL-13 and NGF had a positive correlation (r=0.506, P<0.01). It was suggested that IL-13 and NGF might be involved in the pathogenesis of SLE and closely correlated with disease activity.
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0.05, both). The mean levels of 5-LO and LTC4-S mRNA expression in active SLE group were significantly higher than those in normal controls respectively (P0.05). Conclusion The levels of 5-LO and LTC4-S mRNA expression in active SLE group increase markedly, which may be involved in the pathogenesis of SLE and provide a valuable scientific basis for the clinical use of specific 5-LO inhibitors and cysteinyl leukotrienes receptor antagonists.
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Objectives To investigate the serum levels of IL-13 and n erve growth factor (NGF) and their clinical significance in patients with system ic lupus erythematosus (SLE). Methods The serum levels of IL-13 and NGF were m easured by ELISA in 35 SLE patients and 15 normal controls. Results The serum levels of IL-13 and NGF in patients with active SLE were both significantly high er than those in patients with inactive SLE (IL-13: 92.69 ? 9.87 pg/mL versus 5 4.22 ? 9.31 pg/mL, P
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Objective:To observe the clinical effect and safety of diammonium glycyrrhetate(DG) in the treatment of psoriasis vulgaris. Methods:48 patients were randornly divided into two groups treated group(28 cases)and controlled group(20 cases). Both were given DG or common drugs, respectively. Results:Effective rate was 67.9%(19/28), mean effect-begining time was 17.42±2.36 days in the treated group, they were significantly increased in comparison with controlled group(Effective rate was 30.0%, mean effect-begining time was 25.65±3.54 days). Any side effect was not occurred in treated group. Conclusion:DG is effective and safe in the treatment patients with psoriasis vulgaris.
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Objective To study the serum sex hormones changes in female patients with acne. Methods The serum levels of testosterone(T), free testosterone(FT)﹑estradiol(E 2) and sex hormone-binding globulin(SHBG) were measured in 50 female patients with acne and 15 normal individuals. Results The result showed that the serum FT levels in the patients were significantly higher than those in normal individuals(P